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Volume 17, Issue 6 (Nov-Dec 2023)
mljgoums 2023, 17(6): 23-26 |
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Esmaeili H, Shams Nateri S, Ebrahimi M. The high prevalent involvement of the left coronary artery in Kawasaki disease patients referred to Gorgan's Taleghani Hospital: A retrospective study. mljgoums 2023; 17 (6) :23-26
URL: http://mlj.goums.ac.ir/article-1-1434-en.html
URL: http://mlj.goums.ac.ir/article-1-1434-en.html
1- Congenital Malformations Research Center, Department of Pediatrics, Taleghani Medical Education Center, Golestan University of Medical Sciences, Gorgan, Iran
2- Children's Research Center, Golestan University of Medical Sciences, Gorgan, Iran , M1355ebrahimi@gmail.com
2- Children's Research Center, Golestan University of Medical Sciences, Gorgan, Iran , M1355ebrahimi@gmail.com
Abstract: (251 Views)
Background: Kawasaki disease (KD) is a febrile systemic vasculitis that affects children. Further research is required due to the disease's significance, consequences, and increasing prevalence. This study aimed to determine the frequency of coronary artery complications in patients with KD referred to Taleghani Hospital (Gorgan, Iran) from 2007 to 2017.
Methods: Between 2007 and 2017, 108 cases with a definitive diagnosis of KD were studied retrospectively. Data were obtained from medical records and the patients' biographical, clinical, laboratory, radiographic, and echocardiographic data.
Results: A total of 108 patients diagnosed with KD were involved in the study, 21 (19.44%) of whom showed coronary artery-associated complications. There was no significant difference in clinical and laboratory findings and coronary artery involvement between male and female groups (P-value < 0.05). Left coronary artery (LCA) involvement and the pattern of vascular involvement as ectasia and aneurysm were significantly higher in the echocardiography of the studied patients (P-value = 0.0001).
Conclusion: Kawasaki disease-related coronary artery complication is more common in children under the age of 3, particularly males, in Gorgan. The LCA is the most common site of coronary artery complications in KD children. The findings can improve the prognosis of KD patients and their related heart diseases.
Methods: Between 2007 and 2017, 108 cases with a definitive diagnosis of KD were studied retrospectively. Data were obtained from medical records and the patients' biographical, clinical, laboratory, radiographic, and echocardiographic data.
Results: A total of 108 patients diagnosed with KD were involved in the study, 21 (19.44%) of whom showed coronary artery-associated complications. There was no significant difference in clinical and laboratory findings and coronary artery involvement between male and female groups (P-value < 0.05). Left coronary artery (LCA) involvement and the pattern of vascular involvement as ectasia and aneurysm were significantly higher in the echocardiography of the studied patients (P-value = 0.0001).
Conclusion: Kawasaki disease-related coronary artery complication is more common in children under the age of 3, particularly males, in Gorgan. The LCA is the most common site of coronary artery complications in KD children. The findings can improve the prognosis of KD patients and their related heart diseases.
Research Article: Research Article |
Subject:
Biochemistry
Received: 2021/09/21 | Accepted: 2022/08/3 | Published: 2024/02/26 | ePublished: 2024/02/26
Received: 2021/09/21 | Accepted: 2022/08/3 | Published: 2024/02/26 | ePublished: 2024/02/26
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.