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Askari A, Rashid Lamir A, Bijeh N, Momeni Moghadam M. Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis. mljgoums. 2017; 11 (6) :1-6
URL: http://mlj.goums.ac.ir/article-1-1019-en.html
1- Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
2- Department of Biology, Faculty of Basic Sciences, Hakim Sabzevari University, Sabzevar, Iran
Abstract:   (12859 Views)
         Background and Objectives: The present study aimed to investigate effects of eight weeks of aquatic exercise and resistance training on plasma neurotrophin-4 (NT-4) levels and NT-4 expression in peripheral blood mononuclear cells (PBMCs) of women with multiple sclerosis (MS).
         Methods: Thirty women with MS were randomly assigned to a resistance-training group, an aquatic exercise group and a control group. After separating plasma and PBMCs from blood samples, level of plasma NT-4 and NT-4 expression was measured after eight weeks of exercise via ELISA and Real-time PCR, respectively.
        Results: The level of plasma NT-4 and NT-4 expression increased significantly following eight weeks of aquatic training and resistance training. 
        Conclusion: Based on the results of the present study, both resistance training and aquatic exercise can increase the level of plasma NT-4 and NT-4 expression in female MS patients. It can be concluded that such trainings could have protective and positive effects on the nervous system of MS patients.
        Keywords: Exercise, Multiple Sclerosis, Neurotrophic Factors, Women.
Full-Text [PDF 549 kb]   (1455 Downloads)    
Research Article: Original Paper |
Received: 2017/11/20 | Accepted: 2017/11/20 | Published: 2017/11/20 | ePublished: 2017/11/20

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