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Bahareh Behfar , Fatemeh Haddadi , Mohammad Reza Sharifmoghadam , Hossein Kamaladini, Masoumeh Bahreini, Azadeh Niknejad ,
Volume 20, Issue 2 (3-2026)
Abstract

Background: The poultry industry produces a large amount of waste, including chicken feathers, which are difficult to decompose and can cause environmental pollution. Keratinase enzymes that degrade keratin may be used in poultry waste bioremediation. The objectives were to screen keratinolytic isolates, identify them, optimize culture conditions, and measure activity.
Methods: Two keratinolytic isolates were screened from poultry waste around Mashhad, Iran. They were identified, culture conditions were optimized, and activity was measured using azokeratin and turbidity absorbance.
Results: The two isolates were identified as Bacillus pumilus and Bacillus tequilensis. The optimal conditions were pH 7.0, 37°C, and 48 h of incubation. The maximum keratinase activity was 120 U/mL and 100 U/mL, respectively.
Conclusion: The two Bacillus isolates showed potential for poultry waste bioremediation and keratinase production applicable to animal feed and cleaning products.

Mahnoosh Fatemi, Elham Safi Najafabadi, Zahra Forouzandeh Shahrakei, Amirhossein Arab Najafabadi, Azita Amiri Baghbadorani,
Volume 20, Issue 4 (9-2026)
Abstract

Probiotics are living microorganisms that are mostly from the family of Lactobacillus and Bifidobacterium bacteria. These microorganisms contribute to the health of the host through various mechanisms such as the production of antimicrobial substances, various inhibitors and competition with pathogenic agents. Although some of the mechanisms of probiotics have not been fully determined, its effect on the prevention and treatment of many diseases such as digestive problems, infections and even cancer has been proven. In addition to the direct effects of probiotics in the field of health, the use of these microorganisms in the field of industry also indirectly affects human health. Therefore, the purpose of this review article is to introduce probiotics and some of their roles in the fields of medicine and industry in improving human health.

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