Search published articles

Showing 4 results for jalali

F Amirkhizi, F Siassi, Sm Ahmadi, M Jalali, S Institute, A Rahimi,
Volume 2, Issue 1 (Spring - Summer 2008[PERSIAN] 2008)

Abstract Background and Objectives: Women of reproductive age are at risk of Iron deficiency. Some Studies reported That There is a relationship between Body indices and iron. Iron overload is also harmful. It enhances the risk of cardiovascular disease which is due to increased Lipid peroxidation. The aim of this study was to investigate the relationship between obesity and iron status in women of reproductive age. Material and Methods: In this case-control study, the relationship between iron status and obesity in women of reproductive age was studied in 35 obese (BMIِ≥30kg/m²) and 35 non-obese (BMI=19-25kg/m²) women matched by age. Demographic data was gathered by a questionnaire. Body weight and height were measured and body mass index (BMI) was calculated for each subject. After taking Venous blood samples and separating plasma, we investigated iron status by measuring hemoglobin, hematocrit, and plasma iron and ferritin concentrations. Results: Although no difference is observed in plasma iron and Total Iron Binding Capacity (TIBC), the results of obese group show significant higher hemoglobin (137 ± 8 versus 129 ± 7 g/L, p<0.05), hematocrit (0.41 ± 0.02 versus 0.38 ± 0.03, p<0.05), and plasma ferritin concentrations (49.3 ± 32.2 versus 28.6 ± 19.7µg/L, p<0.001). In addition, BMI was positively correlated with hemoglobin (rho=0.29, p<0.001), hematocrit (rho=0.28, p<0.001), and plasma ferritin concentrations (rho=0.39, p<0.0001). Conclusion: we conclude that obese women of reproductive age have higher iron stores than the non-obese women. Therefore, obese- reproductive women are at low risk of depleting iron stores. On the other hand, systematic iron-fortification programs may enhance the prevalence of iron overload in these subjects. Keywords: Obesity, iron status, reproductive age women
Sh Shabani, Ar Sadeghi Mahoonak, H Jalali,
Volume 8, Issue 2 (summer 2014[PERSIAN] 2014)

Abstract Background and Objective: Cream pastry, because of their ingredients, making process and preserving conditions are susceptible to many types of microbes. This study was conducted to determine the level of contamination of pastry cream in Gorgan. Material and Methods: The randomly selected samples (N = 450) were tested according to national standards for microbial tests and then the data was analyzed. Results: The level of contaminations for Enterobacteriaceae and Staphylococcus aureus was 56% and 43.3%, respectively. The highest contamination occurred in summer with Enterobacteriaceae (N= 113) and the lowest in spring with Staphylococcus aureus (N= 40). Also microbial contamination in different types of cream pastries showed the maximum level in cream puff (90%) and the minimum level in roll pastry (30.6%). Conclusion: There is a significant difference in infection rate between different samples. The infection rate in this study is more than the prevalence of past studies. Keywords: Cream Pastry, Enterobacteriaceae, Staphylococcusaureus, Gorgan
Mohammad Taghvaie, N, Jalali, Mt, Ghasemi Falavarjani, M, Shahbazian, Bb, Saki, A,
Volume 9, Issue 2 (may,jun 2015[PERSIAN] 2015)


        Background and Objective: According to recent changes in diagnostic criteria for diabetes, the harmonization of results obtained from various methods and systems by considering their accuracy and precision is essential. This study aimed to evaluate the accuracy, precision and consensus of some routine laboratory glucose kits in comparison with Hexokinase reference method.


           Material and Methods: The participants were 38 diabetic patients with fasting blood sugar (FBS) ≥126 mg/dl, nine prediabetic patients with FBS of 100-125 mg/dl, 15 non-diabetic people with FBS of 60-100 mg/dl and 9 hypoglycemic patients with FBS of ≤60 mg/dl. Their FBS were measured by four routine laboratory glucose kits:    Glucose oxidase on BT3000 analyzer with an open system and Hexokinase reference method on a close system (COBAS INTEGRA®400plus analyzer, Roche kit). Accuracy and precision were determined and compared with reference method.

         Results: Glucose oxidase methods showed a good agreement with the reference method, in Correlation Coefficient>0.99. based on  regression analysis, the  slope of 1.114 for Pars Azmoon, 1.105 for Bionik, 1.121 for Elitech and 1.087 for Human were reported (P<0.05). Error of the mean for ParsAzmoon was 12.79, for Bionik 10.86, for Elitech 12.58 and for Human were 8.46. Coefficient of Variation   showed more imprecision for Bionik and Human kits.

       Conclusion: given the same almost standard errors, standard devisions and regression analysis, the precision in four methods is the same but in comparison with Hexokinase, reference method has not the accuracy.

          Keywords: Blood Glucose, Glucose Oxidase, Hexokinase, Methods, Consensus

Mohammad Taha Jalali, Hajie Bibi Shahbazian , Mohammad Reza Afsharmanesh , Rohollah Mousavi Dehmordi , Azadeh Saki ,
Volume 10, Issue 2 (Mar,Apr2016 2016)


        Background and Objective: The current challenge of diabetes mellitus is to prevent its complications. These complications are directly associated with hyperglycemia in diabetics. The HbA1c measurement is essential for long-term glycemic control. Synchronization of HbA1c measurement is important in order to avoid discrepancies between results reported by laboratories. This study aimed to evaluate the accuracy, precision and agreement of five HbA1c measurement methods with HPLC reference method.

       Methods: HbA1c levels of 55 samples were measured using six methods of microcapillary electrophoresis (Sepia), enzymatic method (Pishtaz Teb), immunoturbidometry (Pars Azmoon), boronate affinity (Nycocard), immunofluorescence (ichroma) and Tosoh G8 HPLC.

       Results: The five tested methods showed a good agreement with the HPLC method with correlation coefficient of less than 95%. Regression testing of HPLC method and other methods showed slope of 0.99 (P<0.05) for Sebia, 1.02 (P<0.05) for Pishtaz Teb, 0.79 (P<0.05) for Pars Azmoon, 0.82 (P<0.05) for Nycocard and 0.89 (P<0.05) for ichroma. Average inaccuracy for the Sebia, Pishtaz Teb, Pars Azmoon, Nycocard and ichroma in comparison with the HPLC reference method were -0.09, -0.004, -0.75, -0.79 and -0.78, respectively.

         Conclusion: The Sebia microcapillary method and Pishtaz teb enzymatic method have appropriate accuracy and precision. Therefore, these methods can be used as alternatives to the HPLC method for HbA1c measurement. Other methods such as Pars Azmoon, Nycocard and ichroma have significant shortcomings in terms of accuracy.


Page 1 from 1     

© 2007 All Rights Reserved | Medical Laboratory Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.