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Huda Jomma Elkheer Jomma, Mohmmed Omer Abaker Gibreel,
Volume 11, Issue 2 (Mar-Apr 2017)
Abstract

ABSTRACT
       Background and Objective: This descriptive study aimed to evaluate the presence and frequency distribution of mosquito species in the city of Port Sudan, Sudan.
       Methods: After collection of 500 adult mosquitoes from different sectors of the city Port Sudan, they were classified using the morphological keys for identification of mosquitoes.
       Results: Overall, 230 Culex quinquefasciatus (46%) were detected in the eastern, central and southern sectors of the city. Culex sitiens (14.2%) were detected only in the central sector. Aedes aegypti (32.2%) were detected in all three sectors. Anopheles funestus (6.6%) were detected in the central and southern sectors.
      Conclusion: Cx. quinquefasciatus and Ae. aegypi are prevalent in all sectors of the city, while Cx. sitiens is prevalent only in the central sector. An. funestus is abundant in the central and southern sectors.
       Keywords: Culicidae, Morphological and Microscopic Findings, Eastern Sudan.

Mohammed Omer Abaker Gibreel , Mubarak El Saeed Elkarsani , Munsour Mohammed Munsour , Hanan Babeker El Taher ,
Volume 12, Issue 6 (Nov - Dec 2018)
Abstract

ABSTRACT
            Background and objectives: This study aimed to characterize the spectrum of β-thalassemia mutations and haplotypes of sickle cell anemia in Beja tribes and other minor groups living in Port Sudan, Sudan.
            Methods: This descriptive cross-sectional study was carried out from March 2011 to July 2013. Overall, 209 anemic patients were screened for hemoglobinopathy by capillary electrophoresis. The subjects were genotyped for β-thalassemia mutation by amplified refractory mutation system and for sickle cell haplotype by restriction-fragment length polymorphism. 
            Results: Of the 209 patients, 29 (13.87%) showed the typical -88(C→T) β-thalassemia mutation and 27 (12.91%) had sickle cell anemia, of whom 15 (55.6%) were heterozygous AS and 12 (44.4%) were homozygous SS. Based on results of the restriction-fragment length polymorphism; all subjects were with Benin haplotype (Benin/Benin).
            Conclusion: Based on the results of this study, it is recommended to perform a potential carrier screening for the -88 (C→T) mutation and sickle cell Benin haplotype by DNA analysis.
            KEYWORDS: Genotyping, Hemoglobinopathies, Thalassemia, Sickle cell disease, Port Sudan.


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