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Dinarvand, Gh, Veis Raygani, A, Ghanbari, N,
Volume 9, Issue 1 (March, April[PERSIAN] 2015)
Abstract

Abstract Background and Objective: T3 resin uptake test indicates the availability of thyroxin binding globulin (TBG), which is the carrier of a large amount of T3 and T4 in blood. We aimed to study the relationship between serum T3 Resin Uptake and serum lipids profile. Material and Methods: The participants aged 14.80 ± 38.29 were both males (59 29.5%) and females (141 70.5 %). T3 Resin Uptake was measured by Immunoassay method and serum lipid profile components (cholesterol, triglycerides, HDL-C, LDL-C, and VLDL) were measured by the kit. Results: Significant negative correlation was observed between serum T3 Resin Uptake and cholesterol, triglycerides and LDL-C (P≤ 0.05), but that was not the case for HDL-C and VLDL. Conclusion: Serum T3 Resin Uptake can be evaluated to assess the risk factors related to cardiovascular disorders. Keywords: Cholesterol, Triglycerides, T3 Resin Uptake, lipoprotein, Lipid Profile
Negin Rezavand, Asad Vaisi-Raygani, Firozeh Vaisi, Maryam Zangneh , Azin Hoshiar , Fariborz Bahrehmand, Amir Kiani, Gholamabass Dinarvand ,
Volume 10, Issue 4 (Jul-Aug 2016 2016)
Abstract

ABSTRACT

        Background and Objective: Nutritional factors and activation of inflammatory pathways are thought to be involved in pathogenesis of preeclampsia in pregnant women. The present study aimed to compare the serum levels of vitamin D and interleukin-6 in healthy pregnant women with those of preeclampsia ones.

        Methods: This case-control study was performed on 120 healthy pregnant women and 120 women with preeclampsia referred to Imam Reza Hospital in Kermanshah. The serum levels of vitamin D and IL-6 were measured by ELISA method. The data was analyzed by SPSS software (version 20) using independent t-test, the P-value of <0.05 was considered as statistically significant.

        Results: There was no statistically significant difference between the mean level of vitamin D in the patients (37.64 ± 29.50 ng/ml) and the controls (40.06 ± 33.20 ng/ml). the serum level of IL-6 in patients with preeclampsia (21.71 ± 32.24 pg/ml) was significantly higher compared to that of  control group (15.04 ± 28.6 pg/ml) (P <0.001).

       Conclusion: Based on the findings of this study, inflammatory factors and cytokines such as IL-6 can be considered as risk factor for preeclampsia. However, more studies with larger sample sizes are required to further evaluate the association of vitamin D levels and risk of preeclampsia.

           Keywords: Pregnancy, Pre-Eclampsia, Vitamin D, Interleukin-6.



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