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Background and Objectives: Asthma is one of the most common respiratory diseases. Inhaled particles that may trigger allergic reactions and air routes are important factors contributing to asthma. This study aimed to determine the abundance of allergens in children with asthma in Gorgan, Iran.
Methods: In this retrospective study, we randomly collected records of all asthmatic patients over five years of age referred to asthma and allergy clinic in Gorgan, Iran. Furthermore, data related to skin prick test were recorded.
Results: The severity of asthma differed significantly between males and females. There was a direct relationship between age and reaction to one allergen. In addition, 18 of 25 (72 %) patients with severe asthma were allergic to more than two allergens. Moreover, the most common allergen was mite (56%).
Conclusion: Mites are the most common allergen among children with asthma in the study area.

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Infective endocarditis is rare in children but can cause significant morbidity and mortality. Streptococcus and Staphylococcus species are the leading causes of this disease. Staphylococcus is more common in people with underlying heart disease, and Streptococcus viridans is more common in people who have had a dental procedure. In general, any fever of unknown origin in children with an underlying heart problem should be carefully evaluated for endocarditis, and empiric therapy should be performed. The main symptoms of the disease include fever, new murmur, deterioration of the previous murmur, hematuria, embolic events, splenomegaly, bleeding splinter, Osler's nodes, Janeway lesion, and Roth spots. One of the important complications of infective endocarditis is cerebrovascular event and stroke. Herein, we describe a 6-year-old girl presented with fever and skin lesions and no history of underlying heart problem or dental procedure. The patient expired after three days of mitral valve infection with S. aureus.

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The current study aimed to introduce key ethical issues related to laboratory-based diagnostics that any individual may encounter during the provision of healthcare services. In a systematic review, relevant studies published on electronic databases including the PubMed, Scopus, Web of Science, Medline and Cochrane Library were collected for the years 1975 to 2020. The ethical issues related to clinical laboratories diagnosis and patients, colleagues, and society in different phases of laboratory testing were surveyed in this study. Considering ethical issues must be prioritized in each clinical laboratory for better dealing with clients, collaborators, and the community.

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Background: Kawasaki disease (KD) is a febrile systemic vasculitis that affects children. Further research is required due to the disease's significance, consequences, and increasing prevalence. This study aimed to determine the frequency of coronary artery complications in patients with KD referred to Taleghani Hospital (Gorgan, Iran) from 2007 to 2017.
Methods: Between 2007 and 2017, 108 cases with a definitive diagnosis of KD were studied retrospectively. Data were obtained from medical records and the patients' biographical, clinical, laboratory, radiographic, and echocardiographic data.
Results: A total of 108 patients diagnosed with KD were involved in the study, 21 (19.44%) of whom showed coronary artery-associated complications. There was no significant difference in clinical and laboratory findings and coronary artery involvement between male and female groups (P-value < 0.05). Left coronary artery (LCA) involvement and the pattern of vascular involvement as ectasia and aneurysm were significantly higher in the echocardiography of the studied patients (P-value = 0.0001).
Conclusion: Kawasaki disease-related coronary artery complication is more common in children under the age of 3, particularly males, in Gorgan. The LCA is the most common site of coronary artery complications in KD children. The findings can improve the prognosis of KD patients and their related heart diseases.