Suresh Jaiswal, Bijay Subedi, Ashmita Sapkota, Pushpa Sharma, Manisha Timilsina, Maheshwor Timilsina, Bishnu Raj Tiwari,
Volume 18, Issue 1 (Jan-Feb 2024)
Abstract
Background: Intestinal infections with Helicobacter pylori mainly occur during childhood. If contracted, these infections may cause chronic gastritis, frequently leading to peptic ulcer disease in later life. This study aims to detect the prevalence of H. pylori infections in patients with active gastritis.
Methods: The study included 150 participants who were consuming daily anti-gastritis drugs to reduce the gas and were considered active gastritis patients and were recruited from Lekhnath 12, now known as Pokhara metropolitan-30, from May 2018 to March 2019. They were screened for H. pylori antibodies for detection of infection by the immunochromatographic rapid detection kit, and the data were analyzed using SPSS 2016.
Results: Serum anti-Helicobacter pylori antibodies were used to detect the presence of Helicobacter pylori in these participants. Among the 150 participants, 54 were males (36%) and 96 were females (64%). The results showed that 47 (31.3%) of the patients were positive for anti-Helicobacter pylori test. The age group 30 to 40 had the highest prevalence of 21 (14.0%). Using public water showed the highest prevalence with a P value of 0.04.
Conclusion: There should be an additional aspect required for the diagnosis and treatment of gastritis, which is the healthcare providers' and patients' awareness of the cause and most efficient treatments for this medical condition. Using only anti-gastritis drugs is not sufficient; treatment against Helicobacter pylori requires the right pathway of treatment by the use of several antibiotics.
Dr Neema Tiwari, Dr Richa Sharma, Dr Prachi Saxena,
Volume 19, Issue 3 (7-2025)
Abstract
Introduction
Nucleated red blood cells (nRBC) are immature erythrocytes whose production is thought to be driven primarily by the interplay of hypoxia and erythropoietin (EPO) synthesis..It is classified as early onset neonatal sepsis(occurring with first 24 hours of life)or late onset neonatal sepsis(occurring after 48-72 hour).
We planned the study with the aim of analysing the cause for presence of nRBCs in peripheral blood of neonates sent for routine workup in the hematology Lab of Dept of Pathology,SMSR,Sharda University
Material and Method
Retrograde analysis of 27 CBC and peripheral blood smears of neonates was done for a period of 1 month and clinical details, parameters for neonatal sepsis(NLR,PLR,LMR,IG) platelet counts and nRBC counts recorded and tabulated. For result tabulation we divided the neonatal samples into two groups 0-1 day and 2- 30 days
Results
The neonates had 17 males and 9 females. The markers for neonatal sepsis NLR ,LMR and IG were more in cases 2-30 days as compared to cases 0-1 day old. nRBCs were also raised in cases between 2-13 days old. We had 3 cases crossing nRBCs level of 200/100 WBC while 2 vases showed nRBC levels of 150/100 WBC.
Conclusion
We conclude that finding nRBCs in peripheral smear is an important indicator of neonatal stress(sepsis/jaundice/hypoxic sepsis).
