This paper should be cited as:Tabandeh A, Organji H, Aarabi M. [βhCG
Serum level in mild preeclampsia and healthy pregnant women].
MLJ.2013;7(1):
βhCG Serum level in mild
preeclampsia and healthy pregnant women
Tabandeh A(PhD)
*1, Organji
H (PhD)2, Aarabi M (PhD)3
1. Assistant
professor of Gynecologist, Golestan
University of Medical Sciences, Gorgan, Iran
2. General Practitioner, Golestan
University of Medical Sciences, Gorgan, Iran
3. Assistant
Professor, Golestan
University of Medical Sciences, Gorgan, Iran
Background
and Objective: Pre-eclampsia is the most common cause of
maternal and neonatal mortality. Recent
studies show that there may be a relationship between chorionic gonadotropine (HCG) and pre-eclampsia. Thus we aimed at assessing the serum
level of βhCG after 28th week of pregnancy in mild preeclampsia
and healthy pregnant women.
Material
and Methods:In this
case-control study, we measured the level of βhCG in 26 pre-eclamptic women and 26 normal pregnant women. The
difference between groups was analyzed by Mann-Whitney test (P≤ 0.05).
Results:The
mean of βhCG in the case (73192 ±
42956 IU/L) and control group (34038 ± 21272 IU/L) is different significantly
(P= 0.001). Considering mother’s age, gestational age and parity, there is a significant
difference between the two groups (P=0.001).
Conclusion:
The results of our study show that the higher level of βhCG,
the greater the risk of preeclampsia.
Key
words: Pre eclampsia, βhCG, Parity
Corresponding Author: Tabandeh A
Email:Tabande_a@yahoo.com
Received
11 dec 2011 Revised 5 Jan 2013 Accepted 14
Jan 2013