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mljgoums 2019, 13(3): 11-13 |
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Hoseinpoor H, Esmaeili D. Evaluation of Antibacterial Effects of Polyurethane- Cinnamomum zeylanicum Nanofiber Scaffolds against Clinical Isolates of Staphylococcus aureus. mljgoums 2019; 13 (3) :11-13
URL: http://mlj.goums.ac.ir/article-1-1199-en.html
URL: http://mlj.goums.ac.ir/article-1-1199-en.html
1- Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute and Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Department of Microbiology and Applied Microbiology Research Center, Systems biology and poisonings institute and Applied Virology Research Center, Baqiyatallah University of Medical sciences, Tehran, Iran
2- Department of Microbiology and Applied Microbiology Research Center, Systems biology and poisonings institute and Applied Virology Research Center, Baqiyatallah University of Medical sciences, Tehran, Iran
Abstract: (4641 Views)
ABSTRACT
Background and Objectives: In recent years, infections caused by antibiotic-resistant strains of Staphylococcus aureus have become a major health issue. It has been suggested that the extract or essential oil of cinnamon tree has antibacterial properties. In this study, we investigated the antibacterial effects of polyurethane-cinnamon nanofibers against clinical isolates of S. aureus.
Methods: Polyurethane-Cinnamomum zeylanicum nanofiber scaffolds were synthesized. Polyurethane nanofiber and cinnamon polymers were also used to prepare the scaffold under the electrospinning process. Infrared spectroscopy, electron microscopy and mechanical tensile test were utilized to assess the scaffolds. Minimum inhibitory concentration of the nanofiber against the bacteria was determined using the broth dilution method according to the Clinical & Laboratory Standards Institute guidelines.
Results: The results of antibiogram test showed that all tested disks were susceptible to S. aureus. Diameter of growth inhibition zone for polyurethane-cinnamon 10% was 41 mm. Minimum inhibitory concentration of the nanofiber against S. aureus isolates was 0.02 μg/mL.
Conclusion: We demonstrated that the polyurethane-cinnamon nanofiber has favorable antibacterial effects against clinical isolates of S. aureus. It is recommended to conduct further studies on the antibacterial effects of this nanofiber on other bacteria.
Keywords: Staphylococcus aureus, Cinnamon, Nano fiber.
Background and Objectives: In recent years, infections caused by antibiotic-resistant strains of Staphylococcus aureus have become a major health issue. It has been suggested that the extract or essential oil of cinnamon tree has antibacterial properties. In this study, we investigated the antibacterial effects of polyurethane-cinnamon nanofibers against clinical isolates of S. aureus.
Methods: Polyurethane-Cinnamomum zeylanicum nanofiber scaffolds were synthesized. Polyurethane nanofiber and cinnamon polymers were also used to prepare the scaffold under the electrospinning process. Infrared spectroscopy, electron microscopy and mechanical tensile test were utilized to assess the scaffolds. Minimum inhibitory concentration of the nanofiber against the bacteria was determined using the broth dilution method according to the Clinical & Laboratory Standards Institute guidelines.
Results: The results of antibiogram test showed that all tested disks were susceptible to S. aureus. Diameter of growth inhibition zone for polyurethane-cinnamon 10% was 41 mm. Minimum inhibitory concentration of the nanofiber against S. aureus isolates was 0.02 μg/mL.
Conclusion: We demonstrated that the polyurethane-cinnamon nanofiber has favorable antibacterial effects against clinical isolates of S. aureus. It is recommended to conduct further studies on the antibacterial effects of this nanofiber on other bacteria.
Keywords: Staphylococcus aureus, Cinnamon, Nano fiber.
Research Article: Original Paper |
Subject:
Sport Physiology
Received: 2019/03/10 | Accepted: 2019/03/10 | Published: 2019/03/10 | ePublished: 2019/03/10
Received: 2019/03/10 | Accepted: 2019/03/10 | Published: 2019/03/10 | ePublished: 2019/03/10
References
1. Boucher HW, Corey GR. Epidemiology of methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2008; 46 Suppl 5: S344-9. doi: 10.1086/533590. [DOI:10.1086/533590]
2. Meskini M, Khaledi A, Esmaeili D. Inhibitory Effects of a Herbal Ointment against Pseudomonas aeruginosa. mljgoums. 2019; 13(1): 1-5. DOI: 10.29252/mlj.13.1.1. [DOI:10.29252/mlj.13.1.1]
3. Rashki M, Ataee A, Alishiri G, Esmaeili D. Molecular Assay of Staphylococcal Enterotoxin E in Synovial Fluid of Patients with Rheumatoid Arthritis. Int J Infect. 2018; e14230. doi: 10.5812/iji.14230. [DOI:10.5812/iji.14230]
4. Argudín MÁ, Mendoza MC, Rodicio MR. Food poisoning and staphylococcus aureus enterotoxins. Toxins (Basel). 2010; 2(7): 1751-73. doi: 10.3390/toxins2071751. [DOI:10.3390/toxins2071751]
5. Abbasi A, Bahador A, Esmaeili D, Mahbubi A, Amiri M, Amiri M. The Study of Inhibitory Effects of Satureja khuzestanica against MDR Isolates of Pseudomonas aeruginosa. International J of Current Microbiology and Applied Sciences. 2014; 2(3): 614-8.
6. Chihara S, Popovich KJ, Weinstein RA, Hota B. Staphylococcus aureus bacteriuria as a prognosticator for outcome of staphylococcus aureus bacteremia: a case-control study. BMC Infect Dis. 2010; 10: 225. doi: 10.1186/1471-2334-10-225. [DOI:10.1186/1471-2334-10-225]
7. Garibaldi J. Media for the enhancement of fluorescent pigment production by Pseudomonas species. J Bacteriol. 1967; 94(5): 1296-9.
8. Hosseini MJ, Khaledi A, Daymad F, Esmaeili D. Evaluation of The Relationship Between class 1 Integrons and Drug Resistance Genes in Clinical Isolates of Pseudomonas aeruginosa. Open Microbiol J. 2016; 10: 188-96. doi: 10.2174/1874285801610010188. [DOI:10.2174/1874285801610010188]
9. Kiedrowski MR1, Horswill AR. New approaches for treating staphylococcal biofilm infections. Ann N Y Acad Sci. 2011; 1241: 104-21. doi: 10.1111/j.1749-6632.2011.06281.x. [DOI:10.1111/j.1749-6632.2011.06281.x]
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