Volume 12, Issue 1 (Jan-Feb 2018)                   mljgoums 2018, 12(1): 37-43 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bijeh N, Askari A, Ramezani S, Askari B. Effect of Eight Weeks of Aerobic Exercise on Iron Status and Coagulation and Immune Indices in Non-Athlete Females. mljgoums 2018; 12 (1) :37-43
URL: http://mlj.goums.ac.ir/article-1-1046-en.html
1- Department of Sport Physiology, Faculty of Physical Education & Sport Science, Ferdowsi University of Mashhad, Mashhad, Iran , bijeh@ferdowsi.um.ac.ir
2- Department of Physical Education, Gorgan Branch , Islamic Azad University, Gorgan, Iran
3- Faculty Member of Physical Education & Sport Science, Payame Noor University, Iran
4- Department of Physical Education, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran
Abstract:   (15233 Views)
 
Background and objectives: The aim of this study was to investigate the effect of eight weeks of aerobic exercise on serum iron, serum ferritin, platelet count, mean platelet volume, and some immunity indices in non-athlete females.
  • In this study, 30 non-athlete females aged 30-45 years were randomly divided into an experimental and a control group. The experimental group was subjected to perform aerobic exercise at 60-70% of maximal heart rate for eight weeks, three sessions per week and one hour per session. Blood parameters were measured before the exercise program and after the completion of program by taking 2 ml blood samples from the venous vein of the participants in the sitting position. Finally, t-test was used to compare the pre-test and post-test means of each group and independent t-test was used to compare the two groups at significance of 0.05.
  • : After eight weeks of aerobic exercise, there was a significant increase in mean platelet volume and a significant decrease in serum iron and ferritin levels in the experimental group (P <0.05). There was a slight decrease in the number of platelets, white blood cells, granulocytes, monocytes and lymphocytes (P<0.05).
            Conclusion: We recommend physical education instructors, athletes and non-athletes to consider iron supplementation during aerobic exercise, and modify appropriate training intensity based on the fitness and age of trainees to prevent risk of anemia.
            KEYWORDS: Aerobic exercise, platelet, iron, ferritin, white blood cell.
 
Full-Text [PDF 586 kb]   (1771 Downloads)    
Research Article: Original Paper |
Received: 2018/02/24 | Accepted: 2018/02/24 | Published: 2018/02/24 | ePublished: 2018/02/24

References
1. Szygula Z. Erythrocyte system under the influence of physical exercise and training. Sports Med. 1990; 10(3):181-97. [DOI:10.2165/00007256-199010030-00004]
2. Rahmaninia F, Damirchi A, Mousavi SH. The comparison of two types of physical activities on serum iron levels, serum ferritin and transferrin receptor in athletic woman. Olympic. 2005; 13(2): 227-231.[Persian] Alikarami H, Nikbakht M, Valipour Dehnou V, Ghalavand A. Effect of 8 Weeks of Continuous Moderate Intensity Aerobic Training on Iron Status in ClubLevel Football Players. Horizon of MedicalSciences.2017;23(2):129-133
3. Ramezanpour MR, Kazemi M. Effect of aerobic training along with iron supplementation on the hemoglobin, red blood cells, hematocrit, serum ferritin, transferring and iron in young girls. Komesh J. 2012; 13(2): 233-239.[Persian]
4. Vashtani S H, Nazem F, Bordar F. The effect of aerobic rehabilitation program on concentration of Ferritin, Iron, TIBC and cardiovascular operation, the young patients suffering from major thalassemia. Guilan Uni Med Sci. 2009; 18(71): 95-102. [Persian]
5. El-sayed M, Ali N, El-Sayed Ali Z. Haemorheology in exercise and training. Sports Med. 2005; 35(8): 649-670. [DOI:10.2165/00007256-200535080-00001]
6. Williams MS, Kickler TS, Vaidya D, Ng'alla LS, Bush DE. Evaluation of platelet function in aspirin treated patients with CAD. J Throm Thrombolysis. 2006; 21(3): 241-247. [DOI:10.1007/s11239-006-6968-4]
7. Aruigemma C, Fattorossi A, Sestito A, Sgueglia GA, Farneti S, Buzonetti A. Relationship between changes in platelet reactivity and changes in platelet receptor expression inducedby physical exercise. Thrombosis Research. 2007; 120(6): 901-909. 23.
8. El-sayed M, Ali N, El-Sayed Ali Z. Aggregation and activation of blood platelets in exercise and training. Sports medicine. 2005; 35(1): 11-22. [DOI:10.2165/00007256-200535010-00002]
9. Singh I, Quinn H, Mok M, Sinclair AG, Hawley JA. The effect of exercise and training status on platelet activation: Do cocoa polyphenols play a rol?. Platel. 2006; 17(6): 361-367. [DOI:10.1080/09537100600746953]
10. Wang JS, Li Y, Chen Y. Effects of exercise training and deconditioning on platelet aggregation induced by elternating shear stress in men. Arterioscler Thromb Vasc Biol. 2005; 25(2): 454-460. [DOI:10.1161/01.ATV.0000151987.04607.24]
11. Li N, He S. Platelet activity, coagulation and fibrinolysis during exercise in healthy males: effects of thrombin inhibition by argatroban and enoxaparin. Arteriosc Thromb and Vasc Biol. 2007; 27: 407-413. [DOI:10.1161/01.ATV.0000253906.19648.ac]
12. Ghanbari Niaki A, Mohammadi S. Effect of 4 Weeks of an Aerobic (RAST) Training on Hematological Changes In Male Kick-Boxers. Journal of Applied Exercise Physiology (Journal of Sports Science). 2009-2010; 5(10): 75-87.[Persian]
13. Hoffman-Goetz L, Pedersen BK. Exercise and the immune system: A model of the stress response? Immunol Today. 1994; 15(8): 345-392. [DOI:10.1016/0167-5699(94)90177-5]
14. Wu HJ, Chen KT, Shee BW, Chang HC, Huang YJ, Yang RS. Effects of 24 h ultra-marathon on biochemical and hematological parameters. World J Gastroenterol. 2004; 10(18): 2711-4. [DOI:10.3748/wjg.v10.i18.2711]
15. Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi F. Dairy consumption is inversely associated with the prevalence of the metabolic syndrome in tehranian adults. The American journal of clinical nutrition. 2005; 82(3): 523-30. [DOI:10.1093/ajcn/82.3.523]
16. Mcfarlin B, Mitchell J, Mcfarlin M, Steinhoff G. Repeated endurance exercise affects leukocyte number but not nkcell activity. Medicine & Science in Sports & Exercise. 2003; 35(7): 130-90. [DOI:10.1249/01.MSS.0000074463.36752.87]
17. Ebrahim Kh, Nurshahi M, Nassrabadi M. A Study of the Effect of Carbohydrate Supplementation Perior to a Maximal Exercise on the Number of White Blood Cells, Glucose and Cortisol in College Female Athletes. Harakat .2005; 25: 21-30. [Persian]
18. Satarifard S, Gaeini AA, Choobineh S. The Effect of Exercise on the Total Number of Blood Leukocytes and Platelets of the Athletes in Cold, Warm and Normal Temperature Conditions. Armaghane-danesh, Yasuj University of Medical Sciences Journal (YUMSJ) .2011; 16(5):433-443. [Persian]
19. Hasani A, Soleimanian K. The effect of progressive endurance training and silymarin consumption on hematolofical parameters. Sci J Iran Blood Transfus Organ.2014; 11(2):155-163. [Persian]
20. Nikseresht A, Fehresti Haghighi Sh, Solhjoo K, Kargar Jahromy H. Effect of maximum activity on the immune system cells in diabetic rats. J Jahrom Univ Med Sci. 2013; 10(4):49-54. [Persian]
21. Hack V, Strobel G, Rau JP, Weicker H. The effect of maximal exercise on the activity of neutrophil granulocytes in highly trained athletes in a moderate training period. Eur J Appl Physiol Occup Physiol. 1992; 65(6): 520-4. [DOI:10.1007/BF00602358]
22. Tayebi M, Agha Alinejad H, Kiadaliri K, Ghorbanalizadeh Ghaziani F. Assessment of CBC in physical activity and sport: a brief review. Sci J Blood Transfus Organ. 2011; 7(4): 249-265. [Persian]
23. Flynn MG, Mackinnon L, Gedge V, Fahlman M, Brickman T. Influence of iron status and iron supple mentation on natural killer cell activity in trained women runners. Inter j sports med apr. 2003; 24(3): 217-22. DOI: 10.1055/s-2003-39095. [DOI:10.1055/s-2003-39095]
24. Kondo S, Fuke T, Tokiwa M, Ryuu H, Yano J, Sakai C, et al. The effects of fitness type exercise on iron status and hematological status for female college student. Rinsho Byori. 1995; 43(9): 953-959.
25. Haghighi AH, Shojae H, Hamedinia MR, Sardar MA. Effect of different volumes of aerobic trainings on iron status in young girls. JSPORT.pec. 2012;15(8): 67-82. [Persian]
26. Di Santolo M, Stel G, Banfi G, Gonano F, Cauci S. Anemia and iron status in young fertile non professional female athletes. Eur J Appl Physiol. 2008; 102(6): 703-709. [DOI:10.1007/s00421-007-0647-9]
27. Dubnov C, Naama W. Prevalence of iron depletion and Top-level Basketball players. Int j sport nut exer metab 2004; 14(1): 30-37. [DOI:10.1123/ijsnem.14.1.30]
28. Schumacher Y, Schmid A, Grath WD, Bulterman D, Berg A. Hematological indices and iron statusin athletes of various sports and performance. Med sci sports exerc. 2002; 34(5), 869-75. [DOI:10.1097/00005768-200205000-00022]
29. Ricci G, Masotti M, De Paoli Vitali E, Vedovato M, Zanotti G. effects of exercise on haematologic parameters, serum iron, serum firritin, redcell 2,3 diphosphoglycerate and creatine contents, and serum erythropoietin in long-distance runners during basal training. acta haematol, 1988; 80(2), 95-8.
30. Ahmadizad S, El-Sayed MS. The effect of graded resistance exercise on platelet Aggregation and Activation. Med Sci Sports Exerc. 2003; 35(6): 1026-32. [Persian] [DOI:10.1249/01.MSS.0000069406.54766.C6]
31. Kawano TA, Aoki N, Homori M, Kawano K, Maki A, Kimura M, et al. Mental stress and physical exercise increase platelet-depondent thrombin genrration. Heart Vessels. 2000; 15(6): 280-8. [DOI:10.1007/s003800070006]
32. Coppola L, Grassia A, Coppola A, Tondi G, Peluso G, Mordente S, et al. Effects of a moderate intensity aerobic program an blood viscosity, platelet aggregation and faibrinlonytic balance in young and middle aged sedentary subjects. Blood Coagul Fibrinlysis. 2004; 15(1): 31-37. [DOI:10.1097/00001721-200401000-00006]
33. Wagner DD, Burger PC. Platelets in inflammation and thrombosis. Thromb Vasc Biol. 2003; 23(12): 2131-7. [DOI:10.1161/01.ATV.0000095974.95122.EC]
34. Weyrich AS, Zimmerman GA. Platelets: signaling cells inside the immune continuum. Trends in Immunology. 2004; 25(9): 489-95. [DOI:10.1016/j.it.2004.07.003]
35. Hulmi JJ, Myllymäki T, Tenhumäki M, Mutanen N, Puurtinen R, Paulsen G. Effects of resistance exercise and protein ingestion on blood leukocytes and platelets in young and older men. Eur J Appl Physiol. 2010; 109(2): 343-53. [DOI:10.1007/s00421-010-1360-7]
36. Tayebi SM, Ghorbanalizadeh Ghaziani F, Ghanbari Niaki A. Effects of a low intensity single session of circuit resistance exercise on hematologic variables in male physical education students. The 5th student's scientific congress on physical education and sport sciences. Mazandaran University of Baboulsar. 2007; 219. [Persian]
37. Tayebi SM, Ghorbanalizadeh Ghaziani F, Ghanbari- Niaki A, Esmaeilzadeh Tolo MR, Hakimi J. Effect of a single session of circuit resistance exercise on serum hematologic changes in male physical education students. the 3rd student's scientific congress on physical education and sport sciences. Ferdowsi university of Mashhad. 2005; 38. [Persian] Ghanbari Niaki A, Tayebi SM, Ghorbanalizadeh Ghaziani F, Hakimi J. Effect of a single Session of Weight-Circuit Exercise on Hematological changes of Physical education Students. Journal of Sports Sciences. 2005; 1(2): 77-88. [Persian]
38. Yilmaz MB, Saricam E, Biyikoglu SF, Guray Y, Guray U, Sasmaz H, et al. Mean platelet volume and exercise stress test. J Thromb Thrombolysis. 2004; 17(2): 115- 20. [DOI:10.1023/B:THRO.0000037666.01018.8c]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2007 All Rights Reserved | Medical Laboratory Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.