Razieh Nazari-Vanani, Naghmeh Sattarahmady, Negar Azarpira, Hossein Heli,
Volume 6, Issue 3 (9-2018)
Abstract
Due to low cost, ease of administration, and lack need for trained personnel, the oral route is the most convenient and accessible way to design different medicines that could be simply consumed by patients. Regardless of the great benefits of this route, the main challenge in the bioavailability of oral medications is gastrointestinal instability. Nanotechnology is used to improve the solubility and bioavailability of poorly water-soluble drugs. The self-nanoemulsifying drug delivery system is an ideal method for improving the solubility and bioavailability of poorly water-soluble drugs. This system is a sustainable combination of drugs, oils, surfactants, and cosurfactants. The combination of these components causes the nanoemulsion of oil in water with the size of droplets in the range of nm, thereby increasing the bioavailability and oral absorption of poorly water-soluble drugs. This system is highly regarded for its benefits and the ability to improve the healing properties of oral medications.
Aliakbar Naghavialhosseini, Mina Pakkhesal, Maryam Ghelichli, Amir Reza Ahmadinia,
Volume 10, Issue 3 (10-2022)
Abstract
A Dentigerous Cyst (DC) is the most common developmental odontogenic cyst that mostly happens in patients between 10 to 30 years of age. It is usually completely asymptomatic and is discovered on a routine radiographic examination or to evaluate the reason for an erupted tooth. Radiographically, this cyst usually presents a well-defined unilocular radiolucency attached to CEJ of an unerupted tooth which can cause displacement of adjacent tooth or resorption.
This article reports a large infected DC in a 10-year-old male patient related to first and second premolar maxillary teeth, which did not erupt or even change their positions. DC was treated successfully by decompression. After 2 years follow up, there was no evidence of recurrence. In conclusion, marsupialization of cyst with no orthodontic intervention or tooth extraction is a conservative, efficient protocol that stimulates bone healing and promotes the eruption of unerupted teeth even if they are deeply crowded.
