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Showing 10 results for Hadi

Morteza Mansoorian, Babak Rastegari-Mehr, Mostafa Ghorbani, Zahra Shafieian, Omid Safari, Sara Moradi, Zahra Delshadi, Aziz Rezapour, Hossein Ansari, Hamid Asayesh,
Volume 3, Issue 1 (5-2015)
Abstract

Background & Objective: Using internet have had a significant impact on the lifestyle changes of internet clients which can affect their health. The aim of this study was to survey the relationship between lifestyle related to internet with loneliness and social support of the internet clients in Ilam University of medical sciences.

Methods: This study was a cross sectional study which was performed in 2014 on 400 university students and personnel of Ilam University of medical sciences using stratified random sampling method.Data collection instrument was a questionnaire comprising of four sections: demographic information, lifestyle related to internet questionnaire , loneliness and social supports questionnaires.All data were analyzed using SPSS software by Mann Withney and Kruscall- Wallis tests and linear regression test.

Results: The linear regression results showed that there was a significant relationship between loneliness and lifestyle related to the internet, gender, marital status, occupational statues and age (P<0.01). There was also a significant relationship between social support and lifestyle related to the internet and age (P<0/05). The results showed that there was a significant relationship between loneliness and social support with marital status, educational degree and internet usage (P<0/01).

Conclusion: According to the significant relation between loneliness and social support with the lifestyle related to the internet, and regarding the inevitability of Internet, it seems more supporting the students and implementing the educational programs for university clients about suitable using of internet is necessary.


Arezou Khosrojerdi, Kazem Mashayekhi, Hadi Zare Marzouni,
Volume 4, Issue 2 (10-2016)
Abstract

Background and Objectives:  The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important component of Turmeric with numerous therapeutic properties. We aimed to review the anti-inflammatory and anti-microbial properties of Curcumin and introduce it as a therapeutic molecule in the present article.

Methods: In this review, 121 articles were selected from authenticated electronic resources and scientific library databases such as Pubmed, Medline, Sciencedirect, WOS, DOAJ, SID, Iranmedex, Magiran and Google Scholar search engine in which Curcumin (Turmeric) had been evaluated as a therapeutic molecule from differeny aspects.

Results: Our findings from the literature revealed that immune responses against infectious and inflammatory factors could be fascilitated by Curcumin. However, the low solubility in water and minimal bioavailability which may lead to poor absorbance from gastrointestinal tract, quick metabolization and elimination from blood circulation are the most important problems during oral consumption.

Conclusion: According to the results of the present review article, Curcumin possesses efficient anti-inflammatory, anti-microbial, anti-viral and anti-parasitic properties. However, the low bioavailability of this substance has limited its treatment properties. Nowadays, several mechanisms have been proposed to increase the bioavailability which can improve its absorption.


Salimi Hadi, Parya Hoseinzadeh, Dr Eghbal Zarei, Zeynab Badal Poor,
Volume 5, Issue 1 (5-2017)
Abstract

Background & Objective:  Health is undoubtedly on of the most important aspects of human life issues and various personal and family factors can have a key role in this issue. The aim of the present study was to predict physical and mental health among married teachers of elementary schools in Karaj city based on components of decision making and problem solving, family solidarity, expression of love and physical appearance.
Methods: The research method was descriptive-analytical. The statistical population included all married teachers of elementary schools in Karaj city in the academic year 2014-2015.  358 individuals were selected based on Morgan table using random cluster sampling. Health Survey Questionnaire (SF36), Dyadic Adjustment Scale (DAS), Samani Family Process Scale (SFPS) and Samani Family Content Scale (SFCS) were used to collect information. The data were analyzed using Pearson correlation and multiple regressions.
Results: Pearson correlation results showed that there was a significant relationship between physical and mental health with components of decision making and problem solving (r= 0/488, P< 0/05), family solidarity (r= 0/474, P< 0/05), expression of love(r= 0/356, P< 0/05) and physical appearance (r= 0/409, P< 0/05). Results of multiple regression showed that components of decision making and problem solving with value %23.7, family solidarity with %18.3, expression of love with %12.6 and physical appearance with %12.8, in total consist %30 of physical variance and mental health.
Conclusion: Decision making and problem solving, family solidarity, expression of love and physical appearance could be used to predict the physical and mental health. By improving these factors the physical and mental health in family members could be increased.

Golnesa Dadkhah, Hadi Bazzazi, Yaghoub Yazdani,
Volume 6, Issue 3 (9-2018)
Abstract

Background and objectives: Rheumatoid arthritis (RA) is a complex and systemic inflammatory disease in which the immune response is disturbed. Single nucleotide polymorphisms (SNPs) in the promoter regions of regulatory cytokines including interleukin-10 (IL-10) may lead to exacerbated immune response and increased risk of RA. Here, we aimed to assess the association of IL-10 -1082 (G/A) (rs1800896) promoter polymorphism with the susceptibility to RA in a population in northeast of Iran.
Methods: A total of 130 RA patients and 128 sex- and age- matched healthy donors were enrolled. The polymerase chain reaction (PCR) was used to amplify the polymorphic regions and restriction fragment length polymorphism (RFLP) technique was applied to detect rs1800896. SPSS 22.0 software was used to analyze data statistically.
Results: Our findings revealed that G allele was significantly associated with the increased risk of RA [OR = 1.88, 95% CI (1.32–2.66), P-value = 0.0001] in patients. Setting AA genotype as the reference, the AG [OR = 2.93, 95% CI (1.68–5.12), P-value = 0.0001] and GG [OR = 5.73, 95% CI (2.30–14.23), P-value = 0.0001] genotypes were significantly associated with RA susceptibility.
Conclusion: The present study suggests that the IL-10 -1082 (G/A) genetic variants are associated with RA susceptibility, but not with the disease activity. While this is the first time to report such an association in a population in northeast of Iran, further studies are needed to confirm these findings.
Sahar Ghovanjzadeh, Hadi Bazzazi, Yaghoub Yazdani,
Volume 6, Issue 3 (9-2018)
Abstract

Background and objectives: Rheumatoid arthritis (RA) is an autoimmune disease with a complex genetic background. The protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a lymphoid specific protein tyrosine phosphatase which is involved in negative regulation of T cell response. Several studies have assessed the association between PTPN22 single nucleotide polymorphisms (SNPs) with RA susceptibility. Here, we aimed to assess the association of PTPN22 (1858 C>T) variant with the susceptibility to RA in northeast of Iran.
Methods: A total of 127 RA patients and 119 age- and sex- matched healthy donors were enrolled. The polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP) technique (PCR-RFLP) was applied to detect PTPN22 (1858 C>T) SNP. SPSS 22.0 software was used to analyze data using relevant statistical tests.
Results: Comparison of allele and genotype frequencies of PTPN22 (1858 C>T) SNP in RA patients and healthy donors revealed no significant association with RA susceptibility.
Conclusion: The present study suggests that the PTPN22 (1858 C>T) genetic variants are not associated with RA susceptibility and disease activity. While this is the first report from northeast of Iran, further studies are needed to confirm these findings
Hadi Salimi, Reza Golvardi Yazdi,
Volume 7, Issue 1 (3-2019)
Abstract

Background and objectives: Dental technicians are in indirect contact with patients. Microorganisms find their way to dental labs through dental impressions. Infection control is a critical procedure to prevent the spreading of diseases. The objective of this study was to evaluate the levels of infection control knowledge and practice and the factors affecting them, in DLs in Yazd – Iran.
Methods: All dental labs in Yazd – Iran were visited and all working technicians were asked to fill questionnaires including knowledge and practice questions. Data was analyzed using t-test via SPSS 17.
Results: Out of 26 filled questionnaires 73% and 50% of the technicians had respectively poor awareness and practice. Regarding adherence to infection control procedures, technicians with higher work experience had significantly higher scores (p value = 0.015). Technicians educated in the field of dental technologies had significantly higher awareness and practice scores (p value= 0.015, 0.029).
Conclusion: Technicians who have been trained at dental schools have higher knowledge and practice regarding infection control. Since dental labs are not obligated to hire only these technicians, workers without related education are occupied in dental labs. This result in the unfortunate status of infection control in dental labs. The poor status of infection control in dental labs can contribute to spread infections to patients and the related healthcare team.
Farzaneh Mirhoseini, Motahare Baghestani, Mohammad Hadi Khajezade, Ali Derafshi, Motahareh Kaboodsaz Yazdi,
Volume 7, Issue 4 (12-2019)
Abstract

Background and objective: Accurate understanding of the anatomy of the inferior alveolar nerve (IAN) and its relation with anatomical landmarks of mandibular molar teeth can reduce the risk of unwanted injuries to the IAN during implant placement.
Methods: 44 CBCTs of patients,who have been reffered to the private oral and maxillofacial radiology center, were examined by a radiologist on the axial, sagittal and coronal planes. Then, the distances between mandibular canal and buccal cortex (BN) and lingual cortex (LN), buccolingual width of the mandibular canal (BL), and the distances between the canal and apex of the first molar (M1N) and second molar of mandible (M2N) were obtained from cross-sectional images. Data were analyzed using SPSS17 software and  Kolmogorov-smirnov and Mann-whitney test.
Results: 21 males and 23 females aged 20 to 50 years old (mean age: 37.8±7.52) were examined. The mean intervals in the regions of first molar in the right and left sides were BN: 4.03,4.06 mm, LN: 2.10,2.58 mm, BL: 2.20,2.20 mm, and M1N: 5.77,5.78 mm and in the second molar region, on the right and left sides were BN: 5.21,5.20 mm, LN: 1.95,1.80 mm and BL: 2.30,2.20 mm and M2N: 3.85,3.55 mm, respectively. There was a significant difference in the mean buccolingual width of mandibular canal in both sides in the region of first molar and left side in the region of second molar between two genders. (P=0.009, P=0.019, P=0.045). Other measurements were not significantly different between two genders (P>0.05).  The age range of patients had no effect on any of the distances and measurements (P>0.05).
Conclusion: buccolingual width of mandibular canal in both sides in the region of first molar and left side in the region of second molar was associated with gender.

Nafiseh Kaviani, Yaghoub Yazdani, Hadi Bazzazi,
Volume 7, Issue 4 (12-2019)
Abstract

Background and objectives: Vitamin D receptor (VDR) has been identified as a susceptibility gene for several autoimmune diseases. This study was designed to investigate the association of VDR gene polymorphisms with the susceptibility to rheumatoid arthritis (RA).
Methods: A case-control study was performed on 130 RA patients and 128 healthy subjects in the north-east of Iran using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR) technique.  
Results: Our findings suggested a significant association of T allele (p=0.01) of TaqI (rs731236), and f allele (p=0.01) of FokI (rs10735810) genetic variants of the VDR gene with RA susceptibility. These significant associations were also found in the T/T genotype of TaqI (p=0.009), and F/f genotype of FokI (P=0.014). The f-T haplotype was more significantly detected in-patients than in healthy controls (p=0.007).
Conclusion: The RA group showed an increase in the f allele and heterozygous F/f genotype and also in the T allele and homozygous T/T and heterozygous T/t genotypes as compared to the control group. Our results demonstrated that polymorphisms of TaqI and FokI in the VDR gene might be involved in the development of RA in an Iranian population.
Sayede Shadi Nazari , Solmaz Norouzi, Mohammad Asghari Jafar-Abadi,
Volume 8, Issue 1 (3-2020)
Abstract

Background and objective: Prevalence and the spread of novel Coronavirus (2019-ncov) cause significant life and financial destruction worldwide and is the cause of severe respiratory infection in humans. The present study briefly reviews the latest information on how the virus is distributed around the world. The main question of the study are: 1- In which geographic regions of the world is the Coronavirus more concentrated? 2- Is the distribution of the Coronavirus geographically stable?
Material and Methods: To answer these questions, we first began collecting and studying the available scientific resources. The required data was obtained from a daily report of confirmed, recovered, and deaths by the Coronavirus separated by state which was collected from January 22, 2020 to Jun 19, 2020. Based on analyzing available patterns in spatial statistics tool in ArcGIS and geostatistical models, we examined how the Coronavirus was distributed around the world.
Results: The spread of the disease is increasing all over the world. Using the results of Map 1, it is seen that the spread of Corona virus has a trend and starts in China and then spreads to the Middle East, Europe and the United States in a linear manner. The results also show that the prevalence of mortality is higher than that of recovery. Central mean and median for all types (Confirmed, Recovered and death) are close to each other. Death mean and median was close to Western countries and Recovered mean and median was close to Eastern countries, while confirmed mean and median was located in the center.
Conclusion: Based on spatial statistics tool in ArcGIS and geostatistical models, we examined how the Coronavirus was distributed around the world. Our results showed that the spread of Corona virus had a trend and started in China and then spread to the Middle East, Europe and the United States in a likely linear manner.

Ghadir Sohrabi, Mahdi Malmir, Ali Asghar Ghafarizade, Tayebeh Faraji,
Volume 9, Issue 1 (3-2021)
Abstract

Background and Objective: Downscale outcome in assisted reproductive techniques (ART) is associated with lipid peroxidation. Melatonin may have beneficial effects against lipid peroxidation and oxidative stress. This work was aimed to evaluate the ameliorative capacity of melatonin versus the passage of time and lipid peroxidation on sperm parameters from the men with ATS in the ART process.
Material and Methods: Semen samples were collected from 50 asthenoteratozoospermic (ATS) men. Samples were divided into control and melatonin group. The test group were incubated with 6 mM melatonin at 2, 4, 6, and 24 hours. Then total and progressive motility, membrane integrity, and Malondialdehyde levels (MDA) were evaluated. Statistical analysis was carried out by SPSS software (repeated-measures ANOVA).
Results: In the control group, total (p<0.01) and progressive (P<0.05) motility and also, membrane integrity (P<0.03) significantly decreased although, MDA levels of sperm significantly increased (*P<0.04). Moreover, in the melatonin group, the mentioned parameters significantly compensated compared to the control group (P<0.05).
Conclusion: In the outcome, melatonin in vitro treatment paves the way for motility and membrane integrity up-regulating in the ATS men.


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