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Showing 2 results for Akhavan Karbassi

Zahra Roustaeizade, Mohamad Hassan Akhavan Karbassi, Khatereh Kheirollahi, Ehsan Babaei Zarch,
Volume 6, Issue 3 (9-2018)
Abstract

Background and objectives: Recurrent aphthous stomatitis (RAS) is a painful ulcerative lesion and its incidence is 20% in the society. Myrtus communis (myrtex) has been effective in the treatment of RAS. In this study, two different concentrations (2.5% versus 5%) of myrtex extract were evaluated to discover the most effective concentration for the treatment of RAS.
Methods: In this randomized, double-blind clinical trial, 60 patients with RAS were evaluated. Thirty patients used myrtex extract 5% and thirty patients used myrtex extract 2.5% (10 drops on lesion for 20 seconds 5 times per day). The severity of pain and burning sensation experienced by patients were measured by visual analogue scale (VAS) and the size of the lesion was estimated by transparent calibrated grid Data analysis was done by running t-test and repeated measures statistical test.
Results: The mean of the largest RAS diameter before treatment was decreased in both groups 1 day and 7 days after treatment (P-value=0.000); however, these differences were not significant in both groups (P-value =0.401). Furthermore, the severities of pain and burning sensation were decreased in both groups (p-value = 0.000). Nevertheless, this decrease was similar in both groups (P-value = 964).
Conclusion: Treatment with different concentrations of myrtex extract is effective in decreasing RAS diameter, pain, and burning sensation. In addition, the therapeutic efficacy of two different concentrations of myrtex extract (2.5% and 5%) was similar in this regard.
Mohammad-Hassan Akhavan Karbassi, Fatemeh Owlia, Henghameh Zandi, Samira Hajimaghsoodi,
Volume 7, Issue 1 (3-2019)
Abstract

Background and objectives: The association of oral micro-organisms with infectious diseases such as bacterial endocarditis is a concern in dentistry. Bacterial endocarditis is a serious disease with a mortality rate of 40%. The present study was conducted to investigate the effect of using chlorhexidine mouthwash on concentrations of some groups of bacteria in gingival sulcus, which is the main contact point of oral flora with circulating blood during scaling.
­­­ Methods: In this Randomized controlled clinical trial, participants were selected among referrals to the department of gingival diseases of Yazd dental school. Participants underwent determining plaque index and after scaling, sampling of the buccal and lingual gingival groove of mandibular central and lateral teeth was performed by paper with walking movement.
Results: participants were 53 patients who divided into two groups. Group A consisted of 27 patients (15 women and 12 men) ranging in age from 21 to 54 years mean of 35) who used 50 mL chlorhexidine mouthwash and Group B consisted of 26 patients (13 females and 13 males) ranging in age from 19 to 51 years old with a mean of 35.76 who used 50 mL normal saline before scaling. Study groups were not significantly different in terms of age, sex and plaque index. (P-values= 0.755, 0.348 and 0.708)
Mann Whitney-Wilcoxon test compared the counted values of Streptococcus viridance and Staphylococcus aureus in control group was significantly higher than the study group. (P-value = 0.000)
Conclusion: according to the results of our study chlorhexidine mouthwash prior to scaling teeth significantly reduced Streptococcus viridance and Staphylococcus aureus colony counts and could be recommended as a complementary agent for antibiotic prophylaxis in high risk patients prone to endocarditis, or as the only agent in moderate risk cardiac patients that antibiotic prophylaxis does not been used.

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