دوره 9، شماره 1 - ( 1-1400 )                   جلد 9 شماره 1 صفحات 16-23 | برگشت به فهرست نسخه ها

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Karimi Fard M, Khajehlandi A. The Effect of Training at Different Temperatures on The Gene Expression of GLUT4 and Insulin Receptor in the Brown Adipose Tissue of Streptozotocin-Induced Diabetic Rats. Jorjani Biomed J. 2021; 9 (1) :16-23
URL: http://goums.ac.ir/jorjanijournal/article-1-780-fa.html
The Effect of Training at Different Temperatures on The Gene Expression of GLUT4 and Insulin Receptor in the Brown Adipose Tissue of Streptozotocin-Induced Diabetic Rats. فصلنامه علمی پژوهشی زیست پزشکی جرجانی. 1400; 9 (1) :16-23

URL: http://goums.ac.ir/jorjanijournal/article-1-780-fa.html


چکیده:   (609 مشاهده)
Background and Objective: Diabetes is one of the health problems in all societies. The aim of the present study was to investigate the effect of a period of training at different temperatures on the gene expression of GLUT_4 and insulin receptor in the brown adipose tissue of diabetic rats.
Material and Methods: In this experimental study, 21 diabetic rats were randomly divided into 3 groups of 7 animals, including: (1) control (C), (2) swimming training at 5° C (S5ºC), and (3) swimming training at 36° C (S36ºC). Water swimming training was performed at 5±2° C and 36±2° C for six weeks, 5 sessions per week and 2-4 minutes per session. Data were analyzed using one-way analysis of variance and Tukey’s post hoc test at the significance level of p≤0.05.
Results: The gene expression of GLUT4 and insulin receptor in the S5º C and S36º C groups was significantly (P = 0.0001) higher than the control group. Also, the gene expression of GLUT4 in the S36º C group was higher than the S5º C group (p = 0.001), and the expression of insulin receptor in the S5º C group was significantly (p = 0.001) higher than the S36º C group.
Conclusion: Swimming training at 5º C and 36º C significantly increased the gene expression of GLUT4 and insulin receptor in the brown adipose tissue of diabetic rats.
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نوع مقاله: تحقیقی | موضوع مقاله: بهداشت
دریافت: 1399/10/16 | پذیرش: 1399/12/3 | انتشار: 1400/1/10

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