Material and Methods: This double-blind clinical trial was conducted on 90 female students, aged 18 to 26, who suffered from PD. They were divided into two groups of case, received lavender essence and Mefenamic acid, and a control group received placebo. Participants were evaluated for the severity and duration of the menstrual pain during the three first-days of the beginning of bleeding before and after receiving drugs. For data analysis, we used descriptive statistics and inferential statistics, using spss software version 11. 

Results: Based on the findings, there is significant difference in pain severity and duration in lavender (P < 0.001) and Mefenamic acid group (P < 0.001). 

Conclusion: Lavender and Mefenamic acid can effectively relieve the menstrual pain severity and duration. Regarding to the side effects of Mefenamic acid, lavender in the form of aromatherapy can be an appropriate substitution.

Material and Methods: This clinical trial was conducted on 44 women with primary dysmenorrhea referred to Hajar hospital in Shahrekord. The participants were randomly allocated to two groups of Agnogol (n=23) to use one 3.2 mg Agnogol pill for three times a day and Mefenamic Acid (n=21) to use 250 mg Mefenamic acid every 8 hours a day for three days. The pain severity was detected by Visual Analogue Scale. We used Independent and Paired t test for comparing the means of quantitative variables and Chi Square for qualitative variables ( P<0.05 ). 

Results: Considering age, menstrual duration, menstrual interval, and pain severity score, there was no significant difference in two groups at the beginning of the study (P>0.05). After intervention, a significant reduction was found in the mean of pain score over time in both Agnogol (P<0.001) and Mefenamic acid (P<0.001) groups, but the difference between two groups was not significant (P>0.05). 

Conclusion: Given the same effect of Agnogol in mitigating dysmenorrhea, we recommend it as an appropriate alternative for Mefenamic acid.